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23 April 2025 A Correction to this paper has been published: Abbreviations BBB: Bloodbrain barrier CNS: Central Nervous System GFAP: Glial fibrillary acidic protein GLP-1R: Glucagon-like peptide-1 receptor HFD: Highfat diet IB4: Biotinylated isolectin B4 Iba-1: Ionized calciumbinding adaptor molecule-1 ND: Normolipid diet NVU: Neurovascular unit SAL: Saline solution SEMA: Semaglutide References Grundy SM, Brewer HB, Cleeman JI, Smith SC, Lenfant C

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Why Proper GLP-1 Storage Is So Important GLP-1 receptor agonists are injectable peptides that mimic natural hormones in the body

CJC-1295 binds to GHRH receptors in the pituitary, stimulating growth hormone release while resisting degradation for extended duration

This effect of GLP-1(2836) was independent of the known GLP-1R and was mediated by a mechanism involving mitochondrial MTP and intracellular sAC in caSMCs and caECs but not CMs