glp-1 epilepsy Repurposing glucagon-like peptide-1 receptor agonists for the treatment of neurodegenerative disorders GLP-1 Agonists and DPP-4 Inhibitors

2024;10:e1841

The enzymatic reaction generally catalyzes the oxidation of PUFAs with the involvement of LOX to produce PE-PUFA-OOH and its derivatives and reactive aldehydes, including Malondialdehyde (MDA) and 4-hydroxynonenal (4HNE), which in turn induce ferroptosis, but these aldehydes, in turn, lead to impaired nucleic acid and protein functions (Pope and Dixon, 2023)

Since then, clinical trials have shown that Ozempic (semaglutide) helps people lose weight

Compounded semaglutide and tirzepatide is not FDA approved for weight loss and is used off label to assist with weight loss

Do not take if you are breastfeeding, as the effects on the infant are not well established