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Resist this urge

Follow-up research (STEP 4) showed that continuing treatment helped maintain the loss, while stopping led to gradual regain for many participants

Weve seen that while both are highly effective in their own right, and both are once-weekly injectable drugs that are approved by the FDA, they operate with distinct mechanismssemaglutide as a GLP-1 receptor agonist and tirzepatide as a dual GLP-1/GIP receptor agonist

Avoid high-fat foods, excessive fiber, spicy dishes, and alcohol, as these can worsen diarrhea while your system adapts to semaglutide's effects

Where Cagrilintide Fits in the Broader Peptide Research Landscape The metabolic peptide research field in 2026 includes several active research threads: Single agonists semaglutide is the reference compound