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Long, Zeng, Shi, Tian, and Chen at West China Hospital of Sichuan University published a systematic review and meta-analysis in Free Radical Research in 2014, pooling data from 35 prospective studies involving 571,511 participants and 72,196 deaths

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Treatment with tirzepatide in adults with pre-diabetes and obesity or overweight resulted in sustained weight loss, and nearly 99% remained diabetes-free at 176 weeks | Eli Lilly and Company

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