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Silencing of miR122 has been shown to upregulate CAT-1 ( SLC7A1 ) expression, and subsequently increase arginine uptake to maintain large intracellular arginine pools for nitric oxide (NO) synthesis, resulting in increased resistance to the multi-kinase inhibitor sorafenib (Kishikawa et al., 2015)

Iron deposition in renal tissue leads to oxidative damage, fibrosis, and inflammatory responses [133, 134]

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She briefly worked at a biotech start-up, both as a technician and HR assistant before joining the Pannunzio Lab as a Junior Specialist in 2022

Diabetic mouse models have shown similar directional benefits