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These brand-name medications have undergone rigorous testing in clinical trials to review their safety, efficacy, and purity

Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (Mounjaro) and chronic weight management (Zepbound) in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

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In contrast, Glp1r expression in eWAT remained below the detection threshold across all experimental groups, thus being undetectable