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In the therapeutic exploration of primary liver cancer (PLC), a TCM preparation produced by Zhejiang Cancer Hospital called Shaoyao Ruangan Mixture (SRM) [composed of 19 Chinese herbs including Herba Hedyotidis, Scutellariae Barbatae Herba, Paridis Rhizoma, Tetrastigma hemsleyanum Diels et Gilg, etc.], could significantly reduce the abundance of Bacteroides in the intestine, which was positively correlated with elevated IL-10 levels and liver cancer development ( Bacteroides to treat PLC, providing an important reference for targeting gut microbiota by TCMs for liver cancer treatment
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