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First, migraine has been increasingly conceptualised as a disorder of brain energy metabolism, in which mitochondrial dysfunction and impaired oxidative phosphorylation are reported between attacks rather than only during them [12, 15, 36, 37]

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However, only about 5% to 18% of the medication is effectively absorbed by the body

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In another study , patients without T2D were more likely to stop using GLP-1 drugs: about 65% discontinued within a year, compared to 46% of those with type 2 diabetes