The body can make it, but demand may rise during illness, injury, intense training or other metabolic stress
That protective biology is one reason it remains relevant to research on tissue stress and treatment-associated damage
In research discussions, it is commonly grouped with ghrelin receptor agonists and growth hormone-releasing peptides, but it is often presented as a more selective compound
PMID: 33 RoseCELanniganJAKimPLeeJJFuSMSungSS
By providing a robust intracellular antioxidant shield, glutathione helps stabilize hyper-reactive mast cells, making them less likely to release histamine in response to minor environmental triggers, thereby reducing the frequency of hives, flushing, and sudden allergic responses