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then a 20 mg/kg dose (the typical therapeutic dose) produces a gut concentration of 6000 M, assuming 75% bioavailability
Serious side effects are rare but can occur, especially if you have one of the risk factors previously mentioned: Inflammation of the pancreas (pancreatitis) Gallbladder problems, including gallstones Increased risk of low blood sugar (hypoglycemia) in patients with type 2 diabetes Kidney problems Serious allergic reactions Changes in vision Increased heart rate while at rest Depression or thoughts of suicide If you have a severe allergic reaction, including swelling of your face, lips, tongue, or throat, trouble swallowing or breathing, severe rash or itching, gaining or feeling dizzy, or a very rapid heartbeat, discontinue treatment and call your health care provider immediately
doi:10.1186/s13075-023-03043-5
What to knowand what to do next How to assess whether its a true semaglutide plateau A true plateau on semaglutide medications like Wegovy isnt something you can spot after just a few slow days
