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FIGURE 6 7.1 Intestinal organoids (IOs) In vitro models previously used to study intestinal nutrient absorption, drug transport and intestinal cell metabolism, such as Caco-2 cells or rodent explant models, have limited value because they are derived from cancer and nonhuman sources, respectively
Serious adverse events were rare and not dose-dependent
This framework also reinforces why supplements aimed at histamine regulation are best viewed as adjunctive support , not alternative therapy, alongside appropriate medical care
PubMed Central, doi:10.2147/BCTT.S129746
Chen F, Cheng R, Chen X, Guo Z
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