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Ric1-Rgp1 is known to serve as the GEF for Rab6 but prior to this study its structure and mechanism were unknown

Subjects enrolled were also negative for HIV and had no history of latent tuberculosis infection or liver function abnormalities

GABA-expressing interneurons become postmitotic at an earlier stage than glutamatergic pyramidal neurons, and they originate from a different source and follow a different migration pathway