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Underdosing due to tablet splitting or improper administration may result in subtherapeutic drug levels, leading to inadequate HbA1c reduction in patients with diabetes or insufficient weight loss in those using the medication for obesity management
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However, retatrutide is still in Phase 3 trials and not yet FDA-approved, so direct real-world comparisons are not yet possible
Its safety profile is well-documented from years of real-world use
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