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After decapitation, the RL4,5,6-DRG and L5-SC were extracted and fixed in 4% paraformaldehyde in 0.1 M phosphate buffer (pH 7.4)
The pharmacological reality of peptide degradation in the GI tract makes meaningful oral absorption extremely unlikely without specialized encapsulation technology (which is still largely experimental for peptides of this size)
For any storage beyond a few weeks, refrigeration is the minimum standard
This process may take several months depending on the individual
B.et al (2006)
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