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The MHRA's stated read is that there is little credible scientific evidence behind the claims, the products are unlicensed, and the marketing has run a long way ahead of the data
10.1016/0021-8707(67)90090-1 J Allergy
2019 May 24;28(6):1779-1784
In addition to this many Doctors may be using the standard lab value reference range instead of the optimal reference range
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