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The agency ordered that the drugmaker, Novo Nordisk, add a warning label to the drug packaging
Yet, intermediate staining was observed in the responsive reporters using intermediate MTX concentrations (data not shown) ruling out the implication of flooding in the response
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In luminescence activity profiling, these variants retained comparable activity on the procaspase-1 (residues 304320) substrate used for evolution as X(PC), but showed no cleavage of IL-1 (residues 529) or ORC1 (residues 691707
In the context of an acute inflammatory state, neutrophils are the initial immune cells that move into tissues, where they secrete chemokines to expedite the recruitment of monocytes into these tissues [130]
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