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Impaired histamine degradation due to reduced enzymatic activity, particularly involving DAO and histamine-N-methyltransferase (HNMT), can contribute to gastrointestinal and inflammatory diseases
The three-step process occurs inside cells, where antioxidant protection is most effective for health
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Both CT and VPA groups showed decreased rearing and crossings on day 2, reflecting habituation, but no significant group differences emerged (Singh 2020)
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