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i.p.) for 10 weeks significantly improved liver and kidney function in db/db mice with diabetic kidney disease and inhibited the expression of pro-inflammatory cytokines (TNF-, caspase-1 and NLRP3) and pro-fibrotic factors (fibronectin, -SMA and collagen I) in the kidney of mice [3]

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Organoids including Matrigel were resuspended in cold PBS and washed twice by centrifugation (600 g) for 10 min at 4 C

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Heart health measures: Systolic blood pressure dropped by about 3 points, a positive sign for long-term heart health