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IGF-1 DES is a 67-amino-acid truncated IGF-1 analog created by deletion of the N-terminal tripeptide, which reduces its binding to IGF binding proteins and increases local tissue bioavailability
You may be drinking plenty of water but still experiencing fatigue, brain fog, muscle cramps, or persistent thirst, which are all the classic signs of inefficient hydration
Gradual dose escalation protocols are used in trials specifically to minimise these effects
doi: 10.1038/s12276-018-0084-3 29 KangZ.ZengJ.ZhangT.LinS.GaoJ.JiangC.et al
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