In homozygous human FcRn Tg32 mice, groups of female and male mice (816 weeks, 21.530.0 g, 5 mice/23 cages/group) were given either IV or SC injection, into the scruff of the neck, of 4 mg/kg of GLP-1 albumin fusions, diluted in DPBS (pH 7.4) (Sigma-Aldrich), respectively
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Compared with the previously published articles, thecontents and purposes of this review are different: (1) Focusing on the therapeutic roles of GLP-1RAs in T2DM, the multiple pathways by which GLP-1 regulates blood glucose are described in a more comprehensive and in-depth manner at the mechanism level