Type 2 diabetics who benefit from GLP-1s are also likely to spend less money on insulin, insulin pumps, and continuous glucose monitors, per Columbia Threadneedle Investments
Similarly, metformin administration commonly induces gastrointestinal disturbances, manifesting as diarrhea, abdominal distension, and nausea 12 , with potentially severe complications including lactic acidosis in rare instances 13
Its mechanism of action includes: Stimulating insulin production from the pancreas Reducing sugar production in the liver Slowing digestion to help with appetite control Supporting long-term weight management Although the precise way semaglutide injection protects kidney function is not fully understood, its benefits in diabetes management and cardiovascular health are well-documented
For instance, insulin is a 51-amino-acid-long peptide hormone that helps your cells take in sugars from your food to use for metabolism and store them in your liver
Phase 2 Trial of Retatrutide for Obesity NEJM summary