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MYCN upregulates the transsulfuration pathway to suppress the ferroptotic vulnerability in MYCN-amplified neuroblastoma

What are the known safety risks of IGF-1 LR3

Yes, when administered under medical supervision

The loss of a major hepatic form of GST, which represents over 3% of total soluble protein (Fountoulakis et al ., 2000), would have been expected to predispose the animals to hepa-totoxicity through a reduction in the glutathione conju-gation of NAPQI (Coles et al ., 1988)