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As of her last visit, she had lost 40 pounds of weight and feels the best she has in years. Her PPI was discontinued, and her asthma therapy was reduced from triple therapy to moderate-dose ICS/LABA and subsequently to low-dose ICS/LABA, with no recurrence of any asthma or gastroesophageal reflux symptoms

This was observed despite increased survival with semaglutide

Consult the FDA and a licensed healthcare professional for current regulations and individualized guidance.

( ad ) Mean (SE) change from baseline in fasting free fatty acids, n = 68 for AMG 133 and n = 6 for placebo at Day 1 (A), fasting triglycerides, n = 6 for AMG 133 and n = 6 for placebo at Day 1 (B), fasting total cholesterol, n = 68 for AMG 133 and n = 6 for placebo at Day 1 (C), fasting LDL, n = 6 for AMG 133 and n = 6 for placebo at Day 1 (D) after multiple ascending doses of AMG 133 or placebo