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P53 down-regulates the expression of SLC7A11 to reduce cystine uptake and enhance the cell sensitivity to ferroptosis
Notably, mutations Q180H and Q207H to hOCTN2 abrogate the sodium sensitivity and the K M for carnitine remains the same with and without sodium 46 , supporting the significance of this dual glutamine motif
But there are times where the body cannot keep up with the demand or is using it faster than it can be made
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