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It binds to a series of receptors known as melanocortin receptors (MCRs)

From initial gastrointestinal protection studies, the research expanded to include wound healing, musculoskeletal repair, neurological effects, cardiovascular applications, and cytoprotection against various toxins [2]

In other words, the gastrointestinal side effects were milder and less frequent than what researchers typically see with GLP-1 and GIP agonists

Immunogenicity of Therapeutic Protein Aggregates

For most hormones and signaling molecules, scientists can trace the entire pathway: the gene that codes for it, the precursor protein its cleaved from, and the receptor it binds to