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Copper transport: Copper is an essential cofactor for lysyl oxidase (collagen cross-linking) and several antioxidant enzymes
We hold doses longer when patients are tolerating, don't push to the maximum dose if a lower dose is delivering the clinical effect, and never escalate just because the calendar says so
Get the reconstitution wrong and you are injecting the wrong dose every single week for months
not a substitute for the prescribers clinical judgment
Blood 1958
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