huberman glp-1 Tim Ferriss's Video on X GLP-1 and Hunger | Ask

Forthcoming clinical trials are welcome and will indeed be the only way to evaluate the impact of IGF-1R targeting in human cancer

Ozempic approved to reduce cardiovascular risk Ozempic (semaglutide 0.5 mg, 1 mg, and 2 mg) previously received FDA approval for cardiovascular health in people with type 2 diabetes after combined results from the SUSTAIN-6 and PIONEER-6 trials showed a 24% reduction in major adverse cardiac events (MACE) such as heart attack, stroke, and other cardiovascular-related deaths

GLP-1s were associated with lower risk of new substance use disorder diagnoses Across alcohol, cannabis, cocaine, nicotine, opioids, and other drug categories, people who started a GLP-1 medication were less likely to receive a new substance use disorder diagnosis over the following 3 years relative to those who started the comparison diabetes medication, sodium-glucose cotransporter-2 inhibitor

This may suggest an increased risk of hypoglycaemia, however, the proximal tubule retains its glucose reabsorption capacity via the action of the SGLT1 when the filtered glucose load falls below ~80 g/day [11]

Table 5 provides a complete list of medications in each class