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and JP23H04921 to Ya.S), AMED-CREST (grant number 24gm1410007h0004 to F.O.), the Takeda Science Foundation (to F.O.), the Naito Foundation (to F.O.), AMED-PRIME (grant number JP21gm6410012 to A.E.), the MEXT Leading Initiative for Excellent Young Researchers (to Yu.S.), Tottori University Research Support Project for the Next Generation (to Yu.S.), and the Grant for International Joint Research Project of the Institute of Medical Science, the University of Tokyo (to Ya.S
Framework of study design for cost effectiveness analysis
The results show a clear dose-response relationship: At 4mg weekly, participants in the Phase 2 trial achieved approximately 17.5% mean body weight reduction over 48 weeks