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Int J Mol Sci 24(5)

doi: 10.20944/preprints202002.0029.v1 420 PivovarovaNBAndrewsSB

Reduce dietary fat temporarily

Another use case for Calocurb might be to team it with a prescription weight loss drug to improve tolerability by leveraging their synergy to step down dosing

3.3 Fat Metabolism While Hexarelin is not a metabolic peptide in the same class as Semaglutide or Tirzepatide, elevated GH/IGF-1 signaling drives: Increased lipolysis (fat breakdown) Enhanced fatty acid oxidation Reduction in visceral adipose tissue Tesamorelin, an FDA-approved GHRH analog, received approval specifically for visceral fat reduction demonstrating that GH-axis stimulation has meaningful metabolic effects