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Both descriptions hint at something important: the pineal gland punches far above its weight
This suggests that whatever muscle loss occurs, it does not dramatically impact muscle strength
The long half-life is driven by albumin binding (greater than 99% bound), reduced DPP-4 degradation due to the Aib8 substitution, and slowed renal clearance of the larger albumin-bound complex
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Mol Nutr Food Res 2013;57(3):483493
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