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By bridging computational intelligence with materials science, researchers are moving toward a future where nanomedicine is not only more personalized and predictive but also more robust and translatable across diverse clinical settings

Am J Clin Nutr 2003

Reduced CII activity has consequences for central carbon metabolism because CII is involved in the conversion of succinate to fumarate within the TCA cycle 73

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However, as we age, NAD+ levels naturally decline, leading to fatigue, cognitive impairment, and a slower metabolism