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Stable liver function during long-term administration of Eltrombopag, a Thrombopoietin receptor agonist, in patients with chronic liver disease

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Compared with the sham-operated group, the protein and mRNA levels of snail, vimentin and N-cadherin were significantly upregulated after UUO establishment, while C3G treatment reduced the increased expression induced by UUO, and protein and mRNA levels of the epithelial marker E-cadherin were significantly decreased, the C3G treatment indeed inhibited this process (Fig