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As a strong antioxidant, glutathione helps manage hyperpigmentation by protecting skin cells from oxidative stress caused by sun exposure, pollution, and environmental damage

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DNMT1 is mainly involved in the maintenance of the pre-existing pattern of DNA methylation during replication, and DNMT3A and DNMT3B are the de novo methyltransferase (80)

Despite these differences, research has shown that even low doses of ionizing radiation produce cellular responses (double stranded breaks, free radical formation, lipid peroxidation, cellular necrosis, apoptosis) that are analogous, albeit smaller, than larger radiation doses [58]

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