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Ongoing Phase 3 trials are evaluating retatrutide in knee osteoarthritis (where weight-independent anti-inflammatory effects have been observed), obstructive sleep apnea, and non-alcoholic steatohepatitis
Further investigation is warranted to determine the optimal dosages and long-term effects of medications for T2DM and identify the variables contributing to heterogeneity through meta-regression analysis, mostly due to differences in study design, patient demographics, and treatment regimes
References Ong KL, et al
Strength Training Routines Complementing Medication-induced Fat Loss After starting tirzepatide, many notice rapid fat loss
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