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A phase II study of temsirolimus (CCI-779) in patients with advanced leukemias

HalderMPetsophonsakulPAkbulutACPavlicABohanFAndersonEet al

Purity from the synthesis process also helps

However, systemic bioavailability from oral dosing remains unquantified in humans, and most healing effects in rodents were shown via injection, not oral route