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233 Sodium-glucose cotransporter-2 (SGLT2) inhibitors are commonly used for type 2 diabetes treatment, and in recent years, SGLT2 inhibitors canagliflozin has been shown to suppress IL-6 and IL-1 levels and MPO enzyme activity in the colon of UC rats by downregulating the expression of NF-B p65, thereby reducing colonic inflammatory cell infiltration and oxidative stress
Both substances are increasingly popular in the United States, often among overlapping populations seeking metabolic health improvements
Guest opinions in Open Forum and Insight are produced by writers with expertise, personal experience or original insights on a subject of interest to our readers
Indeed, many experts have debunked the trend on social media, including dietitian Taylor Grasso (@simplyhealthyrd) whose video has more than 346,400 views and 7,500 likes on TikTok
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