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Type 1 diabetes is characterised by autoimmune destruction of insulin-producing cells, with the result that the person is either absolutely or relatively insulin-deficient
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S2CID 16400885
Glutamine inclusion in the TCA cycle highlights its essential function for energy production in fast-dividing cells including cancer cells and immune cells
This powerful mechanism drives weight loss but can also reduce bowel movement frequency, causing constipation in roughly one in five patients during the first weeks of therapy
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