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4.2 Stimuli-responsive nanoplatforms for spatiotemporal drug release The TME of osteosarcoma exhibits distinct physicochemical features, including acidic pH, elevated glutathione levels, and hypoxia, that can be exploited for stimuli-responsive drug release (45, 59)
Tesamorelin therapy has been shown to trigger lipolysis, or fat burning, especially around the abdominal area [9]
Months 5 to 6: Most patients report the clearest visual changes in this window, with improvements in abdominal definition and overall leanness
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