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Tirzepatide (Mounjaro, Zepbound) targets two pathways (GLP-1 and GIP), producing greater weight loss in head-to-head studiesroughly 20% body weight loss on tirzepatide vs 15% on semaglutide
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Enhanced glutaminolysis in cancer cells ensures a stable supply of glutamate and -KG via sequential deamination processes inside mitochondria
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