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[PubMed: 39868309] [Free PMC Article] Fletcher MM, Keov P, Truong TT, et al
The authors found that all approved therapies outperformed placebo, with semaglutide and tirzepatide achieving more than 10% total body weight loss and additional benefits across cardiometabolic and obesity-related outcomes
Studies have shown that the incidence of vomiting with dulaglutide (a GLP-1RA) was reported at 17%, compared to 12% with exenatide, indicating variability among different GLP-1 agonists
The 5-HT3 receptor is essential for exercise-induced hippocampal neurogenesis and antidepressant effects
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