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Cell Mol Immunol 22:8396

It is not scheduled under the Controlled Drugs and Substances Act but remains an unapproved compound with significant risks

Moreover, the addition of either 3.5 mM ManNAc or sialic acid to the pneumococcal cultures grown on galactose led to a significant decrease in the expression of galK (3.4 0.07 and 6.6 0.03, n = 4 for ManNAc and sialic acid, respectively) and lacD (4.5 0.15 and 2.8 0.25, n = 4 for ManNAc and sialic acid, respectively) compared to the growth on galactose

The sensitivity of R 4 parameters ( k p4 ) with respect to model OCR output is in good accordance with the AIC/BIC analysis, confirming the need for the R 4 reaction, which is present in both the triad and the comproportionation models, but not in the reduced model

Thompson A, Maibach HI