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From experimental data of kinetic measurements of BRET, following vehicle and baseline corrections, quantification of induced responses from individual peptide concentrations was determined by calculating the net area under curve from the 10 min response (AUC 0-10min) ) in GraphPad Prism version 9.0.1 (GraphPad Software Inc., San Diego, CA)
Cryopreservation may reduce viability and immunomodulatory activity, while donor age and disease can affect mitochondrial fitness and paracrine function
However, the effectiveness of traditional treatment methods for osteosarcoma is still limited, as the 5-year survival rate falls within the range of 60% to 70%
h , Volcano plots of the fold change in mitochondrial metabolite abundance (log 2 ) versus P values (-log) from HEK-293T SLC25A39 knockout cell line expressing a vector control or SLC25A40 cDNA
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