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Early studies in obese individuals showed some reductions in body fat mass, but findings are not consistent across trials: In one clinical trial, AOD9604 did not demonstrate statistically significant weight loss compared to placebo, suggesting its fat-burning effects may be modest without lifestyle intervention (summary of trials)

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Saleh Ahmed AS

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doi: 10.1016/j.immuni.2022.10.014 16 AppledornDMPatialSMcBrideAGodbehereSVan RooijenNParameswaranNet al

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10) indicate a complex interaction between NFT derivatives and the Nrf2 pathway

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References Mohiba Tareen, MD

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