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TMAO t 1/2 was estimated by fitting linear regression to log-transformed concentrations over the final three time points of each curve, corresponding to the terminal elimination phase, following standard log-linear pharmacokinetic modeling methods

Future research, including longitudinal studies and post-market surveillance, will be critical in providing clearer guidance on semaglutides role during pregnancy

Management stated in Q1 that a significant majority of GLP-1 revenue came from personalized dosages