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The Tat (YGRKKRRQRRR) peptide can cross the cell membrane, but a modified Tat-polyethylene glycol-b-cholesterol (Tat-PEG-b-col) peptide, which can form microparticles, was used to deliver drugs across the BBB
These peptides, supplied in sterile glass vials, must be reconstituted with either bacteriostatic water or sterile water both available in the full range of research supplies
The decision to continue treatment long-term must be individualized and reassessed periodically
Ultimately, I tailor treatment to the individual
Micronutrient gaps get wider
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