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Some patients dont get enough B12 from their diet, while others cant absorb it properly due to digestive issues
Two estimands will be more prevalent in future publications for weight management RCTs: the treatment policy estimand (estimated using MI) and the trial product estimand (estimated using MMRM)
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While effective, these medications may alter nutritional intake and gastrointestinal functionparticularly during early treatment phases or dose adjustments
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