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A dermatologist can usually confirm a benign macule with a simple visual examination, sometimes complemented by a dermatoscope
Other digestive issues include: Diarrhea or loose stools Constipation Stomach pain or discomfort Vomiting Reduced appetite (which contributes to weight loss) Heartburn or acid reflux Most of these side effects feel strongest during the first month and gradually decrease over time
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10.1016/S0025-7753(14)70103-4 62
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