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It does this by slowing gastric emptying, reducing glucose production in the liver, and enhancing insulin secretion from pancreatic beta cells when levels of glucose are high

For obesity without binge eating, the primary dysfunction appears to be impaired GLP-1 action, characterized by reduced satiety signaling and relatively rapid gastric emptying

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For example, the cerebellum exhibits relatively high glutathione activity, which contributes to its enhanced resistance to oxidative damage