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These CpG sites exhibit different distributions across the genome, and CpG dinucleotide clusters are found at expected frequencies, forming regions known as CpG islands (CGI) (Figure 1)

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Here are a few examples: Iron supplements Bismuth subsalicylate (found in Pepto-Bismol) Dark-colored foods like blueberries, black licorice, and dark chocolate Foods high in iron, such as red meat and spinach Unlike tarry stool, black stool from these sources doesnt feel sticky

Here are some lifestyle modifications that can help alleviate symptoms: Low histamine diet : Avoid foods high in histamine, such as fermented foods, fish, and citrus fruits

doi:10.1084/jem.20161653