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For subcutaneous semaglutide, begin with 0.25 mg weekly for 4 weeks, increase to 0.5 mg weekly, then to 1.0 mg after another 4 weeks if needed [4]
Rybelsus was studied as a stand-alone therapy and in combination with other diabetes treatments, including metformin, sulfonylureas (insulin secretagogues), sodium-glucose co-transporter-2 (SGLT-2) inhibitors, insulins and thiazolidinediones, all in patients with type 2 diabetes
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